Entrapment of the median nerve in the carpal tunnel, which is formed by the flexor retinaculum and the carpal bones; this syndrome may be associated with repetitive occupational trauma, wrist injuries, amyloid neuropathies, rheumatoid arthritis, acromegaly, pregnancy, and other conditions; symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally; impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur.

Carpal tunnel syndrome (CTS) is a nerve compression syndrome associated with the collected signs and symptoms of compression of the median nerve at the carpal tunnel in the wrist. Carpal tunnel syndrome usually has no known cause, but there are environmental and medical risk factors associated with the condition...